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21 posts and 16,940 words published in the last year
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Adult Patients with Acute Dyspnea
One of the chief presenting complaints in the emergency department is dyspnea. The review article in question instructs clinicians on how to evaluate dyspnea and its etiology1. The …
Soliloquy of the Nameless
The rail separates the pine grove steeped in haze from the serene lake, which stretches to the base of a mountain barely visible beyond the winter haze, the apparition of a white …
Founders of EBM
When reading papers and textbooks, the following figures appear most repeatedly. Sackett Sackett was one of the founders of EBM. Contributions include several seminal RCTs showing …
Lessons from Basic Statistics for Clinician: Hypothesis Testing
Uncertainty comes with a study of modest power (too small a sample size to rule out chance)—one that does not produce a result below the 0.05 significance threshold but may still, …
Pharmaceutical Companies and Misleading Claims in the Literature
I remember reading somewhere—I forget where—that these companies will often publish their material in-house (i.e. rather than going to an independent, well-established journal, …
Grading Drugs Within a Class: Level 1-2 of Evidence
The paper1 categorizes levels of evidence for comparison of drugs within a class from 1-4, each with unique threats to validity. Levels 3 and 4 will be discussed later. Superiority …