Surrogate endpoints in clinical trials
Surrogate endpoints are endpoints that are not directly related to the clinical outcome of interest but are used as a substitute for it. They are often used in clinical trials to …
3 min
Medicine
Recent Posts
AAS Trial 1 / Standard Operating Procedure
Quantification of Iron in E. coli Cells by Atomic Absorption Spectroscopy PurposeThis protocol describes the use of atomic absorption spectroscopy (AAS) to quantify iron in an E. …
5 min
Lehr Lab
JAMA on how to read clinical trials
There’s a series from JAMA that goes over how to read clinical trials. The series is written by individuals who are widely recognized in the field of evidence-based medicine. …
6 min
Medicine
Colony Counting using YOLOv8n
Model used is YOLOv8n pretrained on colonies1, but optimized for our use. The process is as follows: flowchart TD A["Load image"] --> B["Find Petri dish with …
2 min
Yep Lab
Calculations for AAS
The reported amount of of iron in WT E. coli is around 10^5 to 10^6 atoms per cell 1. Converting atoms per cell to micrograms per gram of cellsUsing \[ 10^5 \,\text{atoms Fe/cell} …
3 min
Lehr Lab
Revision to the Biofilm Assay: The Bladder Cell Invasion Protocol
Since we were having issues with the biofilm formation, as expounded upon in a previous post, Dr. Yep decided to make some revisions to the protocol. This post will be a brief …
3 min
Yep Lab