Founders of EBM
When reading papers and textbooks, the titular figures appear most repeatedly. SackettSackett was one of the founders of EBM. Contributions include several seminal RCTs showing …
3 min
Posting activity
23 posts and 14,249 words published in the last year
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Recent Posts
Lessons from Basic Statistics for Clinician: Hypothesis Testing
Uncertainty comes with a study of modest power (too small a sample size to rule out chance)—one that does not produce a result below the 0.05 significance threshold but may still, …
2 min
Pharmaceutical Companies and Misleading Claims in the Literature
I remember reading somewhere—I forget where—that these companies will often publish their material in-house (i.e. rather than going to an independent, well-established journal, …
2 min
Medicine
Grading Drugs Within a Class: Level 1-2 of Evidence
The paper1 categorizes levels of evidence for comparison of drugs within a class from 1-4, each with unique threats to validity. Levels 3 and 4 will be discussed later. Superiority …
3 min
Medicine
JAMA Literature Series
Assuming the Drug Class Effect
It is understood, broadly speaking, that drugs of the same class confer the same merits/risks, though one may be more efficacious and safer than the other. The drug class paper …
2 min
Medicine
JAMA Literature Series
Lab Recipes
Swarming Media 1% (w/v) tryptone 0.5% (w/v) yeast extract 1% (w/v) NaCl 0.6% (w/v) Eiken agar (not regular agar!) 0.5% (w/v) Glucose (add from a sterile 20% glucose solution after …
1 min
Yep Lab